Bear in mind that you're going to need a MediaWiki plugin so that the user's information can be pushed into MW so that the higher level logic does sensible things. You can't just use mod_ntlm or flip on IWA in IIS.
That is specifically what the HTTP auth plugin, and the remote user plugin were written for. If the user doesn't want anything more than authentication (that apache, or IIS can handle), these plugins are perfectly fine.
V/r,
Ryan Lane