And trying to decide what a notable or significant artwork might be seems to smack with the same problems that plagues Wikipedia in terms of notability of people.

The Foundation already daily receives complaints about deletion of articles about various artists, works of art, web comics.

I can understand where Mindspillage et al are getting at (Guernica or similar works are notable, others aren't) but, as you rightly point out, this will be fraught with questions like "why do you have a picture of <insert artist's work> and not of <insert artist's work>"?

This will be especially acute since, at least I suspect, some comics are much better known among the people who read Wikipedia than some allegedly "important" modern artists.

And finally, I don't see why we make an exemption for modern artists and museums, who live off self-promotion.