The FAIR Digital Objects Conference 2022 http://fdo2022.org/, sponsored by the FAIR Digital Objects Forum http://fairdo.org/, will bring together for the first time at this scale key technical, scientific, industry, and science‐policy stakeholders with the aim to boost the development and implementation of FDOs worldwide. The in-person conference will take place 26-28 October at Naturalis Biodiversity Center https://www.naturalis.nl/ (Leiden, The Netherlands) and conclude with the formal signing and publication of the Leiden Declaration on FAIR Digital Objects. The conference has the potential to be a milestone event, initiating the systematic transformation FAIR data into a reality. Registration https://www.aanmelder.nl/fdo2022/subscribe is now open and you are encouraged to participate by answering our Call for Abstracts https://www.fdo2022.org/programme/call-for-abstracts (new extended deadline 10 Jul 2022).