120px|High resolution computed tomography (HRCT) images of the lower chest in a 16 year-old boy with diffuse panbronchiolitis
Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production. The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent. DPB occurs more often in males, and usually begins around age 40. It was recognized as a distinct new disease in the early 1960s, and was formally named "diffuse panbronchiolitis" in 1969. If left untreated, DPB progresses to bronchiectasis, an irreversible lung condition that involves enlargement of the bronchioles, and pooling of mucus in the bronchiolar passages. The eventual result of untreated DPB can lead to respiratory failure and heart problems. Daily treatment of DPB with macrolide antibiotics such as erythromycin eases symptoms and increases survival time, but the disease has no known cure. (more...)
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Read the rest of this article: http://en.wikipedia.org/wiki/Diffuse_panbronchiolitis
_______________________________ Today's selected anniversaries:
1759:
The British Museum in London, today containing one of the largest and most comprehensive collections in the world, opened to the public in Montagu House, Bloomsbury. http://en.wikipedia.org/wiki/British_Museum
1919:
A large molasses tank in Boston, Massachusetts, burst and a wave of molasses rushed through the streets , killing 21 people and injuring 150 others. http://en.wikipedia.org/wiki/Boston_Molasses_Disaster
1937:
Spanish Civil War: Nationalists and Republican both withdrew after suffering heavy losses, ending the Second Battle of the Corunna Road. http://en.wikipedia.org/wiki/Second_Battle_of_the_Corunna_Road
1975:
Portugal signed the Alvor Agreement with UNITA, the MPLA, and the FNLA, ending the Angolan War of Independence. http://en.wikipedia.org/wiki/Alvor_Agreement
1993:
Salvatore "The Beast" Riina, one of the most powerful members of the Sicilian Mafia, was arrested after three decades as a fugitive. http://en.wikipedia.org/wiki/Salvatore_Riina
_____________________________ Wiktionary's word of the day:
penny farthing (v): A type of bicycle popular in the 19th century, with the front wheel far larger than the rear one http://en.wiktionary.org/wiki/penny_farthing
___________________________ Wikiquote quote of the day:
Those whose conduct gives room for talk
Are always the first to attack their neighbors. --Molière http://en.wikiquote.org/wiki/Moli%C3%A8re
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