Sertraline (known under the trade names Zoloft and Lustral) is an antidepressant of the selective serotonin reuptake inhibitor class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily used to treat clinical depression in adult outpatients as well as obsessive-compulsive, panic and social anxiety disorders in both adults and children. In 2007 it was the most prescribed antidepressant on the U.S. retail market. The efficacy of sertraline for depression is similar to that of older tricyclic antidepressants, but its side effects are much less pronounced. Differences with newer antidepressants are subtler and also mostly confined to side effects. Evidence suggests that sertraline may work better than fluoxetine (Prozac) for some subtypes of depression. Sertraline is highly effective for the treatment of panic disorder but is inferior to cognitive behavioral therapy when applied to obsessive-compulsive disorder. Sertraline shares the common side effects and contraindications of other SSRIs, with high rates of nausea, diarrhea, insomnia, and sexual side effects; however, it does not cause weight gain, and its effects on cognition are mild.

Read the rest of this article: http://en.wikipedia.org/wiki/Sertraline

_______________________________ Today's selected anniversaries:

1523: Gustav Vasa became King of Sweden, marking the end of the Kalmar Union. (http://en.wikipedia.org/wiki/Gustav_I_of_Sweden)

1683: Oxford University's Ashmolean Museum, the world's first university museum, opened. (http://en.wikipedia.org/wiki/Ashmolean_Museum)

1933: The first ever drive-in theater opened in Pennsauken, New Jersey, United States. (http://en.wikipedia.org/wiki/drive-in_theater)

1944: World War II: The Invasion of Normandy, the largest amphibious military operation in history, began with Allied troops landing on the beaches of Normandy in France. (http://en.wikipedia.org/wiki/Invasion_of_Normandy)

1982: A war in Lebanon began when Israeli forces invaded southern Lebanon to root out members of the Palestine Liberation Organization. (http://en.wikipedia.org/wiki/1982_Lebanon_War)

2005: The U.S. Supreme Court delivered its landmark legal decision in Gonzales v. Raich, allowing the U.S. Congress to ban medical marijuana even in states that approve its use. (http://en.wikipedia.org/wiki/Gonzales_v._Raich)

_____________________ Wiktionary's Word of the day:

Ucalegon: (dated) A neighbor whose house is on fire or has burned down. (http://en.wiktionary.org/wiki/Ucalegon)

_____________________ Wikiquote of the day:

I can be forced to live without happiness, but I will never consent to live without honor. -- Pierre Corneille (http://en.wikiquote.org/wiki/Pierre_Corneille)