The examples you cite seem like good ideas and I support them.
I
would also suggest considering how the Wikidata ontologies we develop fit into
established ontologies in the Semantic Web. For example, the OBO
Foundry (
http://www.obofoundry.org/) is by far the world's most
widely used group of biomedical ontologies [1, 2]. Those ontologies are
rooted in the Basic Formal Ontology (BFO). OWL helps a great deal in being interoperable with those works, but a further ontological commitment tends to be needed for easy compatibility.
Is your gene-disease interaction ontology compatible with BFO, and the OBO ontologies rooted in it?